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anti-survivin, anti-Bcl-2, anti-P-glycoprotein siRNAs-loaded nanoscale coordination polymers particles colloid

Based on

1 Articles
2015 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

nanoscale coordination polymers particles

Type Nano Material
Formula
Role core
2

anti-P-glycoprotein siRNA

Type Biomolecule
Formula
Role layer
3

anti-Bcl-2 siRNA

Type Biomolecule
Formula
Role layer
4

anti-sisurvivin siRNA

Type Biomolecule
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
cisplatin release in PBS solution dependent on cysteine concentration

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
adenocarcinoma A2780 cells

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • anti-sisurvivin siRNA
  • anti-P-glycoprotein siRNA
  • anti-Bcl-2 siRNA
See all (4)
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Product

anti-survivin, anti-Bcl-2, anti-P-glycoprotein siRNAs-loaded nanoscale coordination polymers particles colloid

Size: not specified

Medium/Support: none

Method 2

Type: Physical formation
Source:
Product

anti-survivin, anti-Bcl-2, anti-P-glycoprotein siRNAs-loaded nanoscale coordination polymers particles colloid

Hydrodynamic diameter: 149.6 - 163.0 nm

Medium: phosphate buffer solution

Support: none

References

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