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S14G-humanin loaded lactoferrin-functionalized polymersomes

Based on

1 Articles
2014 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

Vacuous

Type
Formula
Role core
2

S14G-humanin

Type Biomolecule
Formula
Role loaded material
3

methoxy-PEG-PLGA

Type Polymer
Formula
Role layer
4

maleimide-PEG-PLGA

Type Polymer
Formula
Role layer
5

2-iminothiolane modified lactoferrin

Type Biomolecule
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
proton concentration dependent on 1

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Applications

Area Application Nanomaterial Variant Source
drug delivery

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Characterization

Method Nanomaterial Variant Source
cryo-electron microscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
rats with amyloid-β<sub>25-35</sub> injected into the bilateral hippocampus

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • methoxy-PEG-PLGA
  • maleimide-PEG-PLGA
  1. fSbRWUcNMkoQ97okO6
  2. 8TYgtpFaHbCAAD59
Product

S14G-humanin loaded lactoferrin-functionalized polymersomes

Outer diameter: ~ 120 nm

Thickness: ~ 10 nm

Medium/Support: none

References

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