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protamine-coated paclitaxel-loaded poly(lactide-co-glycolide)-b-poly(ethylene glycol)-b-poly(lactide-co-glycolide) nanoparticles

Based on

1 Articles
2015 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

poly(lactide-co-glycolide)-b-poly(ethylene glycol)-b-poly( lactide-co-glycolide)

PLGA-b-PEG-b-PLGA
Type Polymer
Formula
Role core
2

Paclitaxel

Plaxicel Abraxane Paxene Taxol PCL PAC PTX PX
Type Single Compound
Formula C47H51NO14
Role loaded material
3

protamine

Type Biomolecule
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
human hepatocellular carcinoma HepG2 cells

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Preparation

Method 1

Type: Physical formation
Source:
  1. eQVK713gVPzk7LI
Product

protamine-coated paclitaxel-loaded poly(lactide-co-glycolide)-b-poly(ethylene glycol)-b-poly(lactide-co-glycolide) nanoparticles

Diameter: 175.8 - 189.2 nm

Hydrodynamic diameter: ~ 100 nm

Medium/Support: none

References

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