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EDB-FN siRNA-encapsulating PEGylated liposomes

Based on

1 Articles
2015 Most recent source

Composition

1

HBS buffer

Type Complex Compound
Formula
Role core
2

EDB-FN siRNA/protamine complex

Type Complex Compound
Formula
Role loaded material
3

[(2R)-3-hexadecanoyloxy-2-[(Z)-octadec-9-enoyl]oxypropyl] 2-(trimethylazaniumyl)ethyl phosphate

1-stearoyl-2- palmitoyl-sn-glycero-3-phosphocholine 1-palmitoyl-2-oleoyl-sn-glycero-3-phos-phocholine 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine 2-oleoyl-1-palmitoyl-sn-glycero-3-phosphocholine palmitoyl-oleoyl-sn-glycero-phosphatidylcholine 1-palmitoyl-2-oleoylphosphatidylcholine palmitoyl oleoyl phosphatidylcholine palmitoyl-oleoyl-phosphatidylcholine palmitoyloleoyl-phosphatidylcholine palmitoyloleoylphosphatidyl choline palmitoyloleoylphosphatidylcholine Zwitterionic phosphatidylcholine L-α-phosphatidylcholine soy phosphatidylcholine phosphatidylcholine phospholipon 90 NG Phospholipon S100 PL S100 Egg-PC soy PC POPC POPS SPC PC EL
Type Single Compound
Formula C42H82NO8P
Role layer
4

cholesterol

Type Single Compound
Formula C27H46O
Role loaded material
5

1-palmitoyl-2-oleoyl-sn-glycero- 3[phospho-rac-(1-glycerol)]

1-palmitoyl-2-oleoyl-sn-glycero- 3[phospho-rac-(1-glycerol)] 1-palmitoyl-2-oleoyl-sn-glycero-3-[phospho-rac-(1-glycerol)] 1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-(1'-rac-glycerol) 1-palmitoyl-2-oleoyl-sn-glycero-3[phospho-rac-(1-glycerol)] 1-palmitoyl-2-oleoyl-sn-glycero-3 phosphoglycerol 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol palmitoyloleoylphosphatidylglycerol palmitoyloleoylphophatidylglycerol POPG
Type Single Compound
Formula C40H77O10P
Role loaded material
6

PEG2000-DSPE

Type Polymer
Formula
Role loaded material

Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • cholesterol
  • [(2R)-3-hexadecanoyloxy-2-[(Z)-octadec-9-enoyl]oxypropyl] 2-(trimethylazaniumyl)ethyl phosphate
  • 1-palmitoyl-2-oleoyl-sn-glycero- 3[phospho-rac-(1-glycerol)]
See all (4)
  1. V0F6BfXyOJje1Bs6NWX1Mp
  2. TByAfu
Product

EDB-FN siRNA-encapsulating PEGylated liposomes

Hydrodynamic diameter: 88 - 118 nm

Medium: DLS medium

Support: none

References

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