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CRGDK peptide-functionalized platinum(IV) complex-loaded glutathione-stabilized gold nanoparticle water dispersion

Based on

1 Articles
2014 Most recent source

Composition

1

gold

Type Single Compound
Formula Au
Role core
2

L-glutathione (reduced)

glutathione (reduced) reduced L-glutathione reduced glutathione L-glutathione γ-Glu-Cys-Gly glutathione L-GSH GSH
Type Single Compound
Formula C10H17N3O6S
Role layer
3

4-({diamino[(3-carboxypropanoyl)oxy]dichloroplatinio}oxy)-4-oxobutanoic acid

cis,cis,trans-diamminedichlorodisuccinato-platinum(IV) bis((3-carboxypropanoyl)oxidanyl)cisplatin c,c,t-[Pt(NH3)2Cl2(OOCCH2CH2COOH)2] dicarboxylic cisplatin(IV) prodrug c,c,t-Pt(NH3)2Cl2(OOCCH2CH2COOH)2 succinic acid-modified cisplatin cis-platinum prodrug cisplatin prodrug Pt(IV)-(COOH)2
Type Single Compound
Formula C8H16Cl2N2O8Pt
Role layer
4

Cys-Arg-Gly-Asp-Lys

CRGDK
Type Single Compound
Formula C22H42N10O7
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
colloidal stability

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
UV

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Biological effects

Biological system Test details Nanomaterial Variant Source
human prostate adenocarcinoma DU-145 cells

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Preparation

Method 1

Type: Chemical synthesis
Source:
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  2. rPkxB4pd3DZo3I
  3. gOBqRR5qTZAxXZDkiWmH2r4I
Product

CRGDK peptide-functionalized platinum(IV) complex-loaded glutathione-stabilized gold nanoparticle water dispersion

Size: 4.5 - 5.9 nm

Medium/Support: none

References

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