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CS100/shSur-pDNA nanocomplex

Based on

1 Articles
2015 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

chitosan-histidine conjugate

CH100
Type Biomolecule
Formula
Role carriers
2

shRNA-generating pDNA

shSur-pDNA
Type Biomolecule
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release dependent on glutathione concentration

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
hepatoma xenografted Kunming mouse

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
Product

CS100/shSur-pDNA nanocomplex

Size: ~ 206 nm

Medium: solution pH 6.8

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
Product

CS100/shSur-pDNA nanocomplex

Size: ~ 147 nm

Medium: solution pH 1.2

Support: none

Method 3

Type: Physical formation
Source:
Starting materials
Product

CS100/shSur-pDNA nanocomplex

Size: ~ 312 nm

Medium: Dulbecco's modified Eagle medium

Support: none

Method 4

Type: Physical formation
Source:
Starting materials
Product

CS100/shSur-pDNA nanocomplex

Size: ~ 324 nm

Medium: phosphate buffer solution

Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • chitosan-histidine conjugate
  • shRNA-generating pDNA
  1. 75avS8xD39vdD8p1
  2. exQmVrUz8
Product

CS100/shSur-pDNA nanocomplex

Size: not specified

Medium/Support: none

References

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