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ICG/DOX-loaded PEG45-PCL60-PNIPAM33 vesicles

Based on

1 Articles
2015 Most recent source

Composition

1

water

Type Single Compound
Formula H2O
Role core
2

poly(ethylene glycol)-poly(ε-caprolactone)-poly(N-isopropylacrylamide) star terpolymer

PEG45-PCL60-PNIPAM33 star terpolymer PEG-PCL-PNIPAM star terpolymer PEG-PCL-PNIPAM star
Type Polymer
Formula
Role layer
3

doxorubicin

adriblastin adriamycin DOX DXR
Type Single Compound
Formula C27H29NO11
Role loaded material
4

sodium 4-[2-[(1E,3E,5E,7Z)-7-[1,1-dimethyl-3-(4-sulfonatobutyl)benzo[e]indol-2-ylidene]hepta-1,3,5-trienyl]-1,1-dimethylbenzo[e]indol-3-ium-3-yl]butane-1-sulfonate

3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide Iindocyanine Green Indocyanine Green indocyanine green IC-Green® ICG IGG IcG
Type Single Compound
Formula C43H47N2NaO6S2
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release dependent on pH

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Applications

Area Application Nanomaterial Variant Source
drug delivery

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
Balb/c mouse

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • poly(ethylene glycol)-poly(ε-caprolactone)-poly(N-isopropylacrylamide) star terpolymer
  • sodium 4-[2-[(1E,3E,5E,7Z)-7-[1,1-dimethyl-3-(4-sulfonatobutyl)benzo[e]indol-2-ylidene]hepta-1,3,5-trienyl]-1,1-dimethylbenzo[e]indol-3-ium-3-yl]butane-1-sulfonate
  • doxorubicin
See all (4)
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  2. NciVlajnTN
  3. Otrrn
Product

ICG/DOX-loaded PEG45-PCL60-PNIPAM33 vesicles

Size: 90.7 - 111.7 nm

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
Product

ICG/DOX-loaded PEG45-PCL60-PNIPAM33 vesicles

Hydrodynamic diameter: 158.2 nm

Medium: DLS medium

Support: none

References

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