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HMw HA-coated MTX-loaded lipid nanoparticles

Based on

1 Articles
2014 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

methotrexate-loaded lipid nanoparticles

MTX loaded lipid NPs
Type Nano Material
Formula
Role core
2

hyaluronan

HMw HA
Type Biomolecule
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
C15BL/6 mouse with subcutaneous B16F10 tumor

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • hyaluronan
  1. 4OSZQtJhl468QbKjppMtMWk54J6nCl0Yy3ryt9kJXdFhmof7SWIxVctfFE
Product

HMw HA-coated MTX-loaded lipid nanoparticles

Diameter: ~ 100 nm

Hydrodynamic diameter: 150 - 228 nm

Medium: phosphate buffer solution

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • hyaluronan
  1. xz6Sqs1eMo2G228enLORsCRFDfJ8AEdlfwOQTTAToXaXwcfQal5CODHKJm
Product

HMw HA-coated MTX-loaded lipid nanoparticles

Diameter: ~ 100 nm

Hydrodynamic diameter: 156 - 178 nm

Medium: phosphate buffer solution

Support: none

References

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