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D-arm ASO [COX II]-encapsulated R8/GALA-modified MITO-Porter

Based on

1 Articles
2015 Most recent source

Composition

1

HEPES buffer

Type Complex Compound
Formula
Role core
2

D-arm modified antisense 2'-OMe RNA

D-arm ASO [COX II]
Type Biomolecule
Formula
Role loaded material
3

(9Z)-9-octadecenoic acid (1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester

(9Z)-9-octadecenoic acid (1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine 1,2-dioleoyl-sn-glycero-3-phosphorylethanolamine 1,2-dioctanoyl-sn-glycero-3-phosphoethanolamine 1, 2-dioleoyl-sn-glycero-3-phosphoethanolamine 1,2-dioleoyl-sn-glycero- 3-phosphoethanolamine 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine 1,2-dioleoylphosphatidylethanolamine dioleoyl phosphatidylethanolamine dioleoylphosphatidylethanolamine Lipoid PE 18:1/18:1 DOPE
Type Single Compound
Formula C41H78NO8P
Role layer
4

sphingomyelin

Type Complex Compound
Formula
Role loaded material
5

stearylated octaarginine

stearylated R8
Type Biomolecule
Formula
Role loaded material
6

cholesterol-GALA

Chol-GALA
Type Biomolecule
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Applications

Area Application Nanomaterial Variant Source
drug delivery

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
human cervix carcinoma HeLa cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • D-arm modified antisense 2'-OMe RNA
  • stearylated octaarginine
  • (9Z)-9-octadecenoic acid (1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester
See all (6)
  1. UnKfbEo3CaI679gbZ7l
Product

D-arm ASO [COX II]-encapsulated R8/GALA-modified MITO-Porter

Hydrodynamic diameter: 68 - 102 nm

Medium: HEPES buffer

Support: none

References

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