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(Asp)4-PLA-(Platin-4)3-PLGA-b-PEG-OH blended nanoparticles in fetal bovine serum/water

Based on

1 Articles
2015 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

(Asp)4-PLA-(Platin-4)3

Type Polymer
Formula
Role raw materials
2

poly(lactic-co-glycolic acid)-b-poly(ethylene glycol)

PLGA-b-PEG-OH
Type Polymer
Formula
Role raw materials

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
colloidal stability dependent on temperature

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
cisplatin resistant human ovarian carcinoma cell line A2780/CP70

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
Product

(Asp)4-PLA-(Platin-4)3-PLGA-b-PEG-OH blended nanoparticles in fetal bovine serum/water

Diameter: 29.1 - 42.5 nm

Hydrodynamic diameter: ~ 70 nm

Medium: fetal bovine serum/water solution

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • poly(lactic-co-glycolic acid)-b-poly(ethylene glycol)
  • (Asp)4-PLA-(Platin-4)3
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  2. lweIU
Product

(Asp)4-PLA-(Platin-4)3-PLGA-b-PEG-OH blended nanoparticles in fetal bovine serum/water

Diameter: 22.5 - 39.7 nm

Medium/Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • poly(lactic-co-glycolic acid)-b-poly(ethylene glycol)
  • (Asp)4-PLA-(Platin-4)3
  1. 40wPbwqEJQU8FfV6fGrGXtH
  2. h5rQr
Product

(Asp)4-PLA-(Platin-4)3-PLGA-b-PEG-OH blended nanoparticles in fetal bovine serum/water

Diameter: 29.1 - 42.5 nm

Medium/Support: none

Method 4

Type: Physical formation
Source:
Starting materials
Product

(Asp)4-PLA-(Platin-4)3-PLGA-b-PEG-OH blended nanoparticles in fetal bovine serum/water

Diameter: 22.5 - 39.7 nm

Hydrodynamic diameter: ~ 55 nm

Medium: fetal bovine serum/water solution

Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • poly(lactic-co-glycolic acid)-b-poly(ethylene glycol)
  • (Asp)4-PLA-(Platin-4)3
  1. dka6GT4oM60G0TtBSESV5Zs
  2. ltksu
Product

(Asp)4-PLA-(Platin-4)3-PLGA-b-PEG-OH blended nanoparticles in fetal bovine serum/water

Diameter: 33.1 - 46.5 nm

Medium/Support: none

References

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