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control nanoagonist

Based on

1 Articles
2015 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

PAMAM dendrimer G4

Type Polymer
Formula
Role carriers
2

C2-terminally aminated CGS21680 / NHS-PEG2000-MAL

Type Polymer
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
In vitro BBB model (DI-TNC1 cells) co-cultured with the endothelial bEnd.3 cells and rat astrocyte (RA) cells

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • C2-terminally aminated CGS21680 / NHS-PEG2000-MAL
  • PAMAM dendrimer G4
  1. FGQ
Product

control nanoagonist

Hydrodynamic diameter: 5.77 nm

Medium: water

Support: none

References

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