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Gd-DOTA-coupled siRNA/HSA replica nanoparticles

Based on

1 Articles
2014 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

human serum albumin

HSA
Type Biomolecule
Formula
Role raw materials
2

luciferase GL3 mRNA-targeting silencing RNA

luciferase GL3 mRNA-targeting siRNA SiLuc
Type Biomolecule
Formula
Role raw materials
3

DOTA-Gd moiety

Type Single Compound
Formula -C16H24GdN4O7
Role graft

Applications

Area Application Nanomaterial Variant Source
diagnostics

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Characterization

Method Nanomaterial Variant Source
atomic force microscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
Photinuspyralis luciferase gene-transfected human lung carcinoma A549 cells CCL-185

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Preparation

Method 1

Type: Chemical synthesis
Source:
  1. 9kbbfn
  2. nACr3
Product

Gd-DOTA-coupled siRNA/HSA replica nanoparticles

Size: not specified

Medium: phosphate buffer solution

Support: none

Method 2

Type: Chemical synthesis
Source:
  1. wGv9NI
  2. JoQOY
Product

Gd-DOTA-coupled siRNA/HSA replica nanoparticles

Size: not specified

Medium: phosphate buffer solution

Support: none

Method 3

Type: Chemical synthesis
Source:
  1. dqAxlq
  2. ubcnS
Product

Gd-DOTA-coupled siRNA/HSA replica nanoparticles

Size: 103 - 129 nm

Medium: phosphate buffer solution

Support: none

Method 4

Type: Chemical synthesis
Source:
  1. ifZNjK
  2. jBtTV
Product

Gd-DOTA-coupled siRNA/HSA replica nanoparticles

Hydrodynamic diameter: 36 - 52 nm

Medium: phosphate buffer solution

Support: none

Method 5

Type: Chemical synthesis
Source:
  1. tErnUG
  2. 0394F
Product

Gd-DOTA-coupled siRNA/HSA replica nanoparticles

Size: 60 - 104 nm

Medium: phosphate buffer solution

Support: none

References

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