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pegylated poly-4-(vinylpyridine) nanoparticles laden with dexamethasone

Based on

2 Articles
1 Patents
2018 Most recent source

Composition

1

PAMAM G3.5 nanoparticles

Type Nano Material
Formula
Role carriers
2

(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one

dexamethasone Dex DEX DXM
Type Single Compound
Formula C22H29FO5
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug diffusion coefficient

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Applications

Area Application Nanomaterial Variant Source
cosmetics/sunscreens/lotions

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
abdominal human skin

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • (8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
  • polyglycerol nanogels
  1. 1naYby9
Product

pegylated poly-4-(vinylpyridine) nanoparticles laden with dexamethasone

Size: not specified

Medium: water

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • (8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
  • βCD grafted polyglycerol nanogels
  1. 5IcNoNw
Product

pegylated poly-4-(vinylpyridine) nanoparticles laden with dexamethasone

Size: not specified

Medium: water

Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • pegylated poly(lactic acid-co-glycolic acid)
  • (8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
  1. Yg3
  2. CWMtGfSn1TzD
Product

pegylated poly-4-(vinylpyridine) nanoparticles laden with dexamethasone

Hydrodynamic diameter: 61.07 - 64.27 nm

Medium: water

Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • (8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
  • pegylated poly-4-(vinylpyridine)
  1. zpa
  2. YvWKt1WCt8tm
Product

pegylated poly-4-(vinylpyridine) nanoparticles laden with dexamethasone

Hydrodynamic diameter: 35.78 - 37.68 nm

Medium: water

Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • (8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
  • pegylated poly-4-(vinylpyridine)
  1. UeENsyL
  2. Z9hIj
Product

pegylated poly-4-(vinylpyridine) nanoparticles laden with dexamethasone

Hydrodynamic diameter: 49.13 - 63.71 nm

Medium: water

Support: none

References

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