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pegylated poly-4-(vinylpyridine) nanoparticles laden with dexamethasone

Based on

1 Patents
2015 Most recent source

Composition

1

pegylated poly-4-(vinylpyridine)

PEG-PVPy
Type Polymer
Formula
Role carriers
2

(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one

dexamethasone Dex DEX DXM
Type Single Compound
Formula C22H29FO5
Role loaded material

Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Or, view sample content

Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • (8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
  • pegylated poly-4-(vinylpyridine)
  1. hxnxe9N
  2. Q5t2c
Product

pegylated poly-4-(vinylpyridine) nanoparticles laden with dexamethasone

Hydrodynamic diameter: 65.39 - 72.45 nm

Medium: water

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • (8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
  • pegylated poly-4-(vinylpyridine)
  1. 61medQJ
  2. fo4exCZQU3US
Product

pegylated poly-4-(vinylpyridine) nanoparticles laden with dexamethasone

Hydrodynamic diameter: 38.29 - 43.89 nm

Medium: water

Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • (8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
  • pegylated poly-4-(vinylpyridine)
  1. xtt
  2. 6dBQnv14AMCh
Product

pegylated poly-4-(vinylpyridine) nanoparticles laden with dexamethasone

Hydrodynamic diameter: 32.47 - 35.47 nm

Medium: water

Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • (8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
  • pegylated poly-4-(vinylpyridine)
  1. Sma0mVS
  2. g9FvI
Product

pegylated poly-4-(vinylpyridine) nanoparticles laden with dexamethasone

Hydrodynamic diameter: 51.52 - 52.86 nm

Medium: water

Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • (8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
  • pegylated poly-4-(vinylpyridine)
  1. xMM
  2. Oljxwr1qr2WO
Product

pegylated poly-4-(vinylpyridine) nanoparticles laden with dexamethasone

Hydrodynamic diameter: 50.79 - 53.47 nm

Medium: water

Support: none

References

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