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doxorubicin-conjugated PDP amine-modified dextran nanovesicles

Based on

1 Articles
2015 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

phosphate buffer solution

PBS
Type Complex Compound
Formula
Role core
2

doxorubicin-conjugated amine-functionalized 3-pentadecylphenol-modified dextran

doxorubicin-conjugated PDP amine-modified dextran DOX-conjugated DEX-IM-PDP DEX-IM-DOX
Type Biomolecule
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release dependent on esterase or serum presence

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Applications

Area Application Nanomaterial Variant Source
drug delivery

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
breast cancer MCF-7 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • doxorubicin-conjugated amine-functionalized 3-pentadecylphenol-modified dextran
  • phosphate buffer solution
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Product

doxorubicin-conjugated PDP amine-modified dextran nanovesicles

Diameter: ~ 200 nm

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
Product

doxorubicin-conjugated PDP amine-modified dextran nanovesicles

Hydrodynamic diameter: 235 - 245 nm

Medium: phosphate buffer solution

Support: none

References

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