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Tie2 siRNA-loaded PG1.C15/cholesterol/1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-mPEG2000 nanoparticles

Based on

1 Articles
2015 Most recent source

Composition

1

C14 epoxide-modified generation 1 poly(propylenimine) dendrimer

C14 epoxide-modified PPI dendrimer G1 DG1.C14
Type Complex Compound
Formula
Role core
2

small interfering ribonucleic acid

Itgb1 siRNA
Type Biomolecule
Formula
Role loaded material
3

1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]

1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-mPEG2000
Type Polymer
Formula
Role layer
4

cholesterol

Type Single Compound
Formula C27H46O
Role loaded material

Applications

Area Application Nanomaterial Variant Source
drug delivery

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
female C57BL/6 mouse

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • cholesterol
  • small interfering ribonucleic acid
  • 1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]
See all (4)
  1. P1EsVp4ppke5QVlKh825YJvTGQ
Product

Tie2 siRNA-loaded PG1.C15/cholesterol/1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-mPEG2000 nanoparticles

Size: not specified

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • cholesterol
  • small interfering ribonucleic acid
  • C15 epoxide-modified generation 1 poly(propylenimine) dendrimer
See all (4)
  1. tS9nth7V32khNUdj5gkBydyLgp
Product

Tie2 siRNA-loaded PG1.C15/cholesterol/1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-mPEG2000 nanoparticles

Size: not specified

Medium/Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • cholesterol
  • small interfering ribonucleic acid
  • 1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]
See all (4)
  1. qRImq4bZZXbOb3DRcwCn00Z2qx
Product

Tie2 siRNA-loaded PG1.C15/cholesterol/1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-mPEG2000 nanoparticles

Size: not specified

Medium/Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • cholesterol
  • small interfering ribonucleic acid
  • 1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]
See all (4)
  1. ohCCKbdQ4LgPYj8byqn3aZCKTj
Product

Tie2 siRNA-loaded PG1.C15/cholesterol/1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-mPEG2000 nanoparticles

Size: not specified

Medium/Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • cholesterol
  • C15 epoxide-modified generation 1 poly(propylenimine) dendrimer
  • small interfering ribonucleic acid
See all (4)
  1. XEmy7FYPafWMA0a5MDUnM4xAym
Product

Tie2 siRNA-loaded PG1.C15/cholesterol/1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-mPEG2000 nanoparticles

Size: not specified

Medium/Support: none

References

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