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Tie2 siRNA-loaded PG3.C15/1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-mPEG2000 nanoparticles

Based on

1 Articles
2015 Most recent source

Composition

1

C16 epoxide-modified poly(amido amine) dendrimer generation 4

C16 epoxide-modified PAMAM dendrimer G4 PG4.C16
Type Complex Compound
Formula
Role core
2

small interfering ribonucleic acid

Tie2 siRNA
Type Biomolecule
Formula
Role loaded material
3

1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]

1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-mPEG2000
Type Polymer
Formula
Role layer

Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Biological effects

Biological system Test details Nanomaterial Variant Source
female C57BL/6 mouse

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • small interfering ribonucleic acid
  • C15 epoxide-modified poly(amido amine) dendrimer generation 3
  • 1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]
  1. oF1QwshN8b8DDWAWZCAvfG60AF
Product

Tie2 siRNA-loaded PG3.C15/1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-mPEG2000 nanoparticles

Size: not specified

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • C14 epoxide-modified poly(amido amine) dendrimer generation 4
  • small interfering ribonucleic acid
  • 1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]
  1. zkmGE2n0sMqG45NZl9G6vW5rmF
Product

Tie2 siRNA-loaded PG3.C15/1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-mPEG2000 nanoparticles

Size: not specified

Medium/Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • small interfering ribonucleic acid
  • C14 epoxide-modified poly(amido amine) dendrimer generation 3
  • 1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]
  1. pu9ROrZG4QFaQ4EJTr7n8ye5TJ
Product

Tie2 siRNA-loaded PG3.C15/1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-mPEG2000 nanoparticles

Size: not specified

Medium/Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • C12 epoxide-modified poly(amido amine) dendrimer generation 4
  • small interfering ribonucleic acid
  • 1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]
  1. shquoytvFyd6hhly58l5lhKkBy
Product

Tie2 siRNA-loaded PG3.C15/1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-mPEG2000 nanoparticles

Size: not specified

Medium/Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • small interfering ribonucleic acid
  • C12 epoxide-modified poly(amido amine) dendrimer generation 3
  • 1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]
  1. JIBLTkZeOv6VmnEXShkxAMHdGU
Product

Tie2 siRNA-loaded PG3.C15/1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-mPEG2000 nanoparticles

Size: not specified

Medium/Support: none

References

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