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indomethacin nanopowder dispersion

Based on

2 Patents
2015 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

(1-(4-chlorobenzoyl)-5-methoxy-2-methyl-3-indoleacetic acid)

3-indoleacetic acid indomethacin indometacin IndOH INC IND IMC
Type Single Compound
Formula C19H16ClNO4
Role raw materials

Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • hydrogenated soy bean lecithin
  • 1,2,3-trihydroxypropane
  • sodium chloride
See all (6)
Product

indomethacin nanopowder dispersion

Diameter: 283 nm

Medium: D-(-)-mannitol/sodium chloride/polyvinylpyrrolidone/hydrogenated soy bean lecithin/glycerin/sodium dodecylsulfate solution in water

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • 1,2,3-trihydroxypropane
  • sodium chloride
  • D-(-)-mannitol
See all (5)
Product

indomethacin nanopowder dispersion

Diameter: 255 nm

Medium: D-(-)-mannitol/sodium chloride/polyvinylpyrrolidone/glycerin/sodium dodecylsulfate solution in water

Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • DK Ester SS™
  • water
  • D-(-)-mannitol
See all (5)
Product

indomethacin nanopowder dispersion

Diameter: 264 nm

Medium: D-(-)-mannitol/sucrose fatty acid ester/sodium carboxymethyl cellulose/sodium dodecylsulfate/hydrogenated soy bean lecithin solution in water

Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • (1-(4-chlorobenzoyl)-5-methoxy-2-methyl-3-indoleacetic acid)
  • polyethylene glycol 400
  • trethalose
Product

indomethacin nanopowder dispersion

Diameter: 454 nm

Medium: trehalose/polyethylene glycol 400/sodium dodecylsulfate solution in water

Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • DK Ester SS™
  • water
  • D-(-)-mannitol
See all (5)
Product

indomethacin nanopowder dispersion

Diameter: 271 nm

Medium: D-(-)-mannitol/sucrose fatty acid ester/sodium carboxymethyl cellulose/sodium dodecylsulfate/hydrogenated soy bean lecithin solution in water

Support: none

References

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