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HDL-Doxorubicin nanoparticles

Based on

1 Patents
2015 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

gold

Type Single Compound
Formula Au
Role core
2

PDP PE/DPPC lipid mixure

Type Complex Compound
Formula
Role layer
3

apolipoprotein A-I

apoA-I
Type Biomolecule
Formula
Role loaded material
4

doxorubicin

adriblastin adriamycin DOX DXR
Type Single Compound
Formula C27H29NO11
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
doxorubicin loading efficiency

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
Burkitt's lymphoma Ramos cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
Product

HDL-Doxorubicin nanoparticles

Hydrodynamic diameter: 15 nm

Medium: water

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • gold
  • apolipoprotein A-I
  • 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[3-(2-pyridyldithio)propionate]
See all (5)
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Product

HDL-Doxorubicin nanoparticles

Size: not specified

Medium/Support: none

References

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