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5-FU-loaded hollow mesoporous SiO2 nanoparticles

Based on

2 Articles
2015 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

Vacuous

Type
Formula
Role core
2

silicon dioxide

silicic oxide silica
Type Single Compound
Formula SiO2
Role layer
3

5-fluoro-2,4(1H,3H)pyrimidinedione

5-Fluorouracil 5-fluorouracil fluorouracil Adrucil® Efudex® adrucil efudex 5-FU 5-Fu 5FU
Type Single Compound
Formula C4H3FN2O2
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release dependent on pH

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Biological effects

Biological system Test details Nanomaterial Variant Source
colorectal cancer SW480 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  1. ccbss
  2. FR3CfA2acK
Product

5-FU-loaded hollow mesoporous SiO2 nanoparticles

Diameter: ~ 100 nm

Hydrodynamic diameter: 164 nm

Pore size: 2.5 nm

Thickness: ~ 10 nm

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  1. FKO0FdoKYxt0FOKNT
  2. sRML7IDD
Product

5-FU-loaded hollow mesoporous SiO2 nanoparticles

Pore size: 2.5 nm

Size: ~ 120 nm

Thickness: 10 nm

Medium/Support: none

References

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