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DOTA-grafted 8-Ad-PAMAM/CD-PEI/Ad-PEG nanoparticles

Based on

1 Patents
2010 Most recent source

Composition

1

adamantane-grafted 1st-generation1,4-diaminobutane core polyamidoamine dendrimer

adamantanamine-grafted polyamidoamine dendrimer octa-Ad-grafted polyamidoamine dendrimer adamantane-grafted PAMAM 8-Ad-PAMAM Ad-PAMAM
Type Single Compound
Formula C152H252N34O20
Role core
2

CD-PEI-DOTA

Type Polymer
Formula
Role core
3

Ad-PEG

Type Polymer
Formula
Role layer
4

[64]copper(II) cation

[64Cu]copper(II) ion 64copper(II) ion copper-64 cation (64) copper ion copper(II) ion copper-64 ion 64Cu isotope 64copper ion copper ion 64Cu2+ ion 64Cu ion 64Cu(2+) 64Cu2+
Type Single Compound
Formula 64Cu2+
Role dopant

Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
C57BL/6 mouse

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • branched polyetyleneamine
  • DOTA-NHS
  1. sfqn1w20j9K98u7XIhkHzDMWNiuwL
Product

DOTA-grafted 8-Ad-PAMAM/CD-PEI/Ad-PEG nanoparticles

Diameter: ~ 30 - 100 nm

Medium/Support: none

References

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