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topical ophthalmic formulation comprising gabapentin and polymer-based nanocarrier

Based on

1 Patents
2015 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

poly(ethyl acrylate-co-methyl methacrylate-co-trimethylammonioethyl methacrylate chloride)

Eudragit RL100
Type Polymer
Formula
Role carriers
2

gabapentin

Type Single Compound
Formula C9H17NO2
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Biological effects

Biological system Test details Nanomaterial Variant Source
Sprague-Dawley rat

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • poly(ethyl acrylate-co-methyl methacrylate-co-trimethylammonioethyl methacrylate chloride)
  1. eRfTIlgowOcKl4KX
Product

topical ophthalmic formulation comprising gabapentin and polymer-based nanocarrier

Size: 71.09 - 72.65 nm

Medium: phosphate buffer solution

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • poly(ethyl acrylate-co-methyl methacrylate-co-trimethylammonioethyl methacrylate chloride)
  1. CETMiY5wKkmgZ6P3
Product

topical ophthalmic formulation comprising gabapentin and polymer-based nanocarrier

Size: 134.4 - 169.8 nm

Medium: phosphate buffer solution

Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • poly(ethyl acrylate-co-methyl methacrylate-co-trimethylammonioethyl methacrylate chloride)
  1. B4ev15eBKNR3gBRR
Product

topical ophthalmic formulation comprising gabapentin and polymer-based nanocarrier

Size: 231.23 - 241.21 nm

Medium: water

Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • poly(ethyl acrylate-co-methyl methacrylate-co-trimethylammonioethyl methacrylate chloride)
  1. IIqSUaAciFDXcq2A
Product

topical ophthalmic formulation comprising gabapentin and polymer-based nanocarrier

Size: 488.65 - 519.13 nm

Medium: phosphate buffer solution

Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • poly(ethyl acrylate-co-methyl methacrylate-co-trimethylammonioethyl methacrylate chloride)
  1. Kt9Zr20CJeC1Ewt5
Product

topical ophthalmic formulation comprising gabapentin and polymer-based nanocarrier

Size: 354.92 - 358.90 nm

Medium: water

Support: none

References

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