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liposomal nanoparticles encapsulating pDNA

Based on

1 Articles
2015 Most recent source

Composition

1

pDNA/protamine

Type Complex Compound
Formula
Role core
2

PEG-stabilized ss-cleavable lipid-like material based on retinoic acid/1-stearoyl-2-oleoyl sn-glycero-3-phosphocholine/cholesterol

PEG-stabilized ssPalmA/SOPC/Chol
Type Complex Compound
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
BALB/cAJcl-nu/nu mouse bearing OS-RC-2 tumor

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
Product

liposomal nanoparticles encapsulating pDNA

Hydrodynamic size: 149.9 nm

Medium: 2-(4-(2-hydroxyethyl)piperazin-1-yl)ethanesulfonic acid

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
Product

liposomal nanoparticles encapsulating pDNA

Hydrodynamic size: 152.2 nm

Medium: 2-(4-(2-hydroxyethyl)piperazin-1-yl)ethanesulfonic acid

Support: none

Method 3

Type: Chemical synthesis
Source:
Starting materials
  • plasmid DNA encoding luciferase
  • protamine
  1. 7xIMhPp1fiPj
  2. qWAAi4M9901MrUQheAEy0PI
Product

liposomal nanoparticles encapsulating pDNA

Size: not specified

Medium/Support: none

Method 4

Type: Chemical synthesis
Source:
Starting materials
  • plasmid DNA encoding luciferase
  • protamine
  1. nUn3m0Lb6p8r
  2. KjSacKt3w1Ds12cx9fUVo7H
Product

liposomal nanoparticles encapsulating pDNA

Size: not specified

Medium/Support: none

References

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