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oligoarginine/siRNA complexes

How does this work?

Based on

1 Articles
2015 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

oligoarginine

STR-R8
Type Biomolecule
Formula
Role carriers
2

glyceraldehyde 3-phosphate dehydrogenase small interfering RNA

GAPDH siRNA
Type Biomolecule
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
particle size

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Characterization

Method Nanomaterial Variant Source
atomic force microscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
hamster ovary cells CHO-K1

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • glyceraldehyde 3-phosphate dehydrogenase small interfering RNA
  • water
  • oligoarginine
Product

oligoarginine/siRNA complexes

Hydrodynamic diameter: 56 - 72 nm

Medium: water

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • glyceraldehyde 3-phosphate dehydrogenase small interfering RNA
  • phosphate buffer
  • oligoarginine
  1. gHEUB
Product

oligoarginine/siRNA complexes

Size: not specified

Medium: phosphate buffer

Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • glyceraldehyde 3-phosphate dehydrogenase small interfering RNA
  • water
  • oligoarginine
Product

oligoarginine/siRNA complexes

Hydrodynamic diameter: 68 - 90 nm

Medium: water

Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • glyceraldehyde 3-phosphate dehydrogenase small interfering RNA
  • water
  • oligoarginine
Product

oligoarginine/siRNA complexes

Hydrodynamic diameter: 71 - 85 nm

Medium: water

Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • glyceraldehyde 3-phosphate dehydrogenase small interfering RNA
  • water
  • oligoarginine
Product

oligoarginine/siRNA complexes

Hydrodynamic diameter: 86 - 90 nm

Medium: water

Support: none

References

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