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polyvinylpyrrolidone/dioctyl sodium sulfosuccinate-coated megestrol acetate nanoparticles

Based on

3 Patents
2015 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

megestrol acetate

Type Single Compound
Formula C24H32O4
Role core
2

polyvinylpyrrolidone

PVP
Type Polymer
Formula
Role layer
3

sodium 1,4-bis(2-ethylhexoxy)-1,4-dioxobutane-2-sulfonate

sodium 1,4-bis(2-ethylhexyl)sulfosuccinate sodium bis(2-ethylhexyl)-sulfosuccinate sodium bis(2-ethylhexyl)sulfosuccinate dioctyl sulfosuccinate sodium salt dioctyl sodium sulfosuccinate Docusate sodium docusate sodium sodium docusate Aerosol OT aerosol OT NaAOT DOSS AOT
Type Single Compound
Formula C20H37NaO7S
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
physical stability dependent on temperature

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
laser diffraction spectroscopy

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • sodium 1,4-bis(2-ethylhexoxy)-1,4-dioxobutane-2-sulfonate
  • megestrol acetate
  • polyvinylpyrrolidone
  1. zKhrZl17CWocDwS1Ca2
Product

polyvinylpyrrolidone/dioctyl sodium sulfosuccinate-coated megestrol acetate nanoparticles

Size: 167 nm

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • sodium 1,4-bis(2-ethylhexoxy)-1,4-dioxobutane-2-sulfonate
  • megestrol acetate
  • polyvinylpyrrolidone
  1. JwApQ8yOZxhzvNGQKPu
Product

polyvinylpyrrolidone/dioctyl sodium sulfosuccinate-coated megestrol acetate nanoparticles

Size: 167 nm

Medium/Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • sodium 1,4-bis(2-ethylhexoxy)-1,4-dioxobutane-2-sulfonate
  • megestrol acetate
  • polyvinylpyrrolidone
  1. YsVF2VDbFzXHOzEqIrL
Product

polyvinylpyrrolidone/dioctyl sodium sulfosuccinate-coated megestrol acetate nanoparticles

Size: 167 nm

Medium/Support: none

References

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