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cationic DMPC nanovesicle formulation

Based on

1 Articles
2014 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

water

Type Single Compound
Formula H2O
Role core
2

(2R)-2,3-bis(tetradecanoyloxy)propyl 2-(trimethylammonio)ethyl phosphate

1,2-dimyristoyl-sn-glycero-3-phosphocholine dimyristoyl-2-hydroxy-sn-glycero-3-phosphocholine 1,2-dimyristoyl-sn-glycero-3-phosphatidylcholine 1,2-dinonadecanoyl-sn-glycero-3-phosphocholine 1,2-dimyristoyl-sn-glycero-3- phosphocholine 1,2-dimyristoyl-sn-glycero-3-phosphocholine 2-dimyristoyl-sn-glycero-3-phosphocholine dimyristoyl-sn-glycero-3-phosphocholine L-α-dimyristoylphosphatidylcholine dimyristoyl phosphatidylcholine dimyristoylphosphatidylcholine di-14:0PC DMPC DMPE
Type Single Compound
Formula C36H72NO8P
Role layer
3

ε-N-palmitoyl lysine methyl ester

Nε-palmitoyl lysine methyl ester PKM
Type Single Compound
Formula C23H46N2O3
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
colloidal stability

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Applications

Area Application Nanomaterial Variant Source
drug delivery

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
3T3 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
Product

cationic DMPC nanovesicle formulation

Diameter: 20 - 150 nm

Hydrodynamic diameter: 216.73 - 242.01 nm

Medium: Dulbecco's modified Eagle medium with fetal bovine serum

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
Product

cationic DMPC nanovesicle formulation

Diameter: 20 - 150 nm

Hydrodynamic diameter: 227.02 - 279.12 nm

Medium: water

Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • ε-N-palmitoyl lysine methyl ester
  • (2R)-2,3-bis(tetradecanoyloxy)propyl 2-(trimethylammonio)ethyl phosphate
  • water
Product

cationic DMPC nanovesicle formulation

Diameter: 20 - 150 nm

Medium/Support: none

References

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