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anti-tissue factor antibody fragment-conjugated DACHPt-loaded MeO-PEG-b-P(Glu)/maleimide-PEG-b-P(Glu) micelles

Based on

1 Articles
2015 Most recent source

Composition

1

MeO-PEG-b-P(Glu)/maleimide-PEG-b-P(Glu) micelles

Type Nano Material
Formula
Role carriers
2

(1,2-diaminocyclohexane)platinum(II) chloride

DACHPt chloride DACHPtCl
Type Single Compound
Formula -C6H14ClN2Pt
Role loaded material
3

anti-tissue factor antibody fragment

anti-TF Fab'
Type Biomolecule
Formula
Role graft

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
diffusion coefficient

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
BALB/c nu/nu mouse with subcutaneous human pancreatic cancer BxPC3 xenograft

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
Product

anti-tissue factor antibody fragment-conjugated DACHPt-loaded MeO-PEG-b-P(Glu)/maleimide-PEG-b-P(Glu) micelles

Hydrodynamic diameter: ~ 32 nm

Medium: water

Support: none

References

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