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anti-TRAIL-receptor 2 monoclonal antibody-modified dacarbazine-loaded polylactic acid nanoparticles

Based on

1 Articles
2011 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

polylactic acid

polylactide PLA
Type Polymer
Formula
Role core
2

dacarbazine

DTIC
Type Single Compound
Formula C6H10N6O
Role loaded material
3

anti-TRAIL-receptor 2 monoclonal antibody

anti-DR5 mAb
Type Biomolecule
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
human malignant melanoma A375 cells

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Preparation

Method 1

Type: Physical formation
Source:
Product

anti-TRAIL-receptor 2 monoclonal antibody-modified dacarbazine-loaded polylactic acid nanoparticles

Hydrodynamic size: 169.9 - 178.1 nm

Medium: water

Support: none

Method 2

Type: Chemical synthesis
Source:
  1. 935
Product

anti-TRAIL-receptor 2 monoclonal antibody-modified dacarbazine-loaded polylactic acid nanoparticles

Size: not specified

Medium/Support: none

References

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