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PTX-loaded chitosan/vitamin E succinate copolymer nanomicelles

Based on

2 Articles
2018 Most recent source

Composition

1

chitosan/vitamin E succinate copolymer nanomicelles

CS-VES nanomicelles
Type Nano Material
Formula
Role carriers
2

5β,20-Epoxy-1,2α,4,7β,10β,13α­ hexahydroxytax-11-en-9-one 4,10-diacetate 2-benzoate 13-ester with (2R,3S)-N-benzoyl-3­ phenylisoserine

Paclitaxel paclitaxel Plaxicel Abraxane Paxene Taxol PCL PTX PAC PX
Type Single Compound
Formula C47H51NO14
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
differential scanning calorimetry

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Biological effects

Biological system Test details Nanomaterial Variant Source
A549 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • lipoic acid-modified pullulan
  • 5β,20-Epoxy-1,2α,4,7β,10β,13α­ hexahydroxytax-11-en-9-one 4,10-diacetate 2-benzoate 13-ester with (2R,3S)-N-benzoyl-3­ phenylisoserine
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Product

PTX-loaded chitosan/vitamin E succinate copolymer nanomicelles

Size: not specified

Medium/Support: none

Method 2

Type: Physical formation
Source:
Product

PTX-loaded chitosan/vitamin E succinate copolymer nanomicelles

Size: not specified

Medium/Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • water
  • chitosan/vitamin E succinate copolymer
  • 5β,20-Epoxy-1,2α,4,7β,10β,13α­ hexahydroxytax-11-en-9-one 4,10-diacetate 2-benzoate 13-ester with (2R,3S)-N-benzoyl-3­ phenylisoserine
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  2. LoJ5WwG
Product

PTX-loaded chitosan/vitamin E succinate copolymer nanomicelles

Hydrodynamic diameter: 364.3 - 366.9 nm

Medium: water

Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • water
  • chitosan/vitamin E succinate copolymer
  • 5β,20-Epoxy-1,2α,4,7β,10β,13α­ hexahydroxytax-11-en-9-one 4,10-diacetate 2-benzoate 13-ester with (2R,3S)-N-benzoyl-3­ phenylisoserine
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  2. cbkSqhk
Product

PTX-loaded chitosan/vitamin E succinate copolymer nanomicelles

Hydrodynamic diameter: 322.8 - 329.8 nm

Medium: water

Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • water
  • chitosan/vitamin E succinate copolymer
  • 5β,20-Epoxy-1,2α,4,7β,10β,13α­ hexahydroxytax-11-en-9-one 4,10-diacetate 2-benzoate 13-ester with (2R,3S)-N-benzoyl-3­ phenylisoserine
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  2. UqHKjwJ
Product

PTX-loaded chitosan/vitamin E succinate copolymer nanomicelles

Hydrodynamic diameter: 379.9 - 381.7 nm

Medium: water

Support: none

References

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