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cationic liposome-coated plasmid DNA/protamine/plasmid DNA nanoparticles

Based on

1 Articles
2012 Most recent source

Composition

1

plasmid DNA/protamine/plasmid DNA nanoparticles

DNA/Pro/DNA nanoparticles DPD nanoparticles DPD
Type Nano Material
Formula
Role core
2

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine/6-lauroxyhexyl lysinate mixture

DOPE/LHLN mixture
Type Complex Compound
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
human liver carcinoma HepG2 cells

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Preparation

Method 1

Type: Physical formation
Source:
Product

cationic liposome-coated plasmid DNA/protamine/plasmid DNA nanoparticles

Diameter: ~ 150 - 200 nm

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • (9Z)-9-Octadecenoic acid (1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester
  • 6-lauroxyhexyl lysinate
  1. sUSo1OttMA6m70V1g7M
  2. CASFG8u16pRx24VxzXf
Product

cationic liposome-coated plasmid DNA/protamine/plasmid DNA nanoparticles

Hydrodynamic diameter: 175.9 - 185.3 nm

Medium: aqueous solution

Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • (9Z)-9-Octadecenoic acid (1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester
  • 6-lauroxyhexyl lysinate
  1. McUaqUrjjMyC1VX89Yu
  2. ektGRnDNRL08iVvqnEn
Product

cationic liposome-coated plasmid DNA/protamine/plasmid DNA nanoparticles

Hydrodynamic diameter: 463.0 - 475.6 nm

Medium: aqueous solution

Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • (9Z)-9-Octadecenoic acid (1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester
  • 6-lauroxyhexyl lysinate
  1. 7Bd9VwNBtXMBIIWETV3
  2. g5tm6UHS7LQgnhPSVLo
Product

cationic liposome-coated plasmid DNA/protamine/plasmid DNA nanoparticles

Hydrodynamic diameter: 155.1 - 161.9 nm

Medium: aqueous solution

Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • (9Z)-9-Octadecenoic acid (1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester
  • 6-lauroxyhexyl lysinate
  1. 2CC1rFxc5zFNVtewLAJ
  2. B8FXi8IjRJXr6lHcz08
Product

cationic liposome-coated plasmid DNA/protamine/plasmid DNA nanoparticles

Hydrodynamic diameter: 131.7 - 137.5 nm

Medium: aqueous solution

Support: none

References

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