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nanoformulation of EFV

Based on

1 Articles
2011 Most recent source

Composition

1

efavirenz

EFV EFZ
Type Single Compound
Formula C14H9ClF3NO2
Role core
2

poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol)

poloxamer-188 P188
Type Polymer
Formula
Role layer
3

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]

1,2-distearoyl-phosphatidylethanolamine-methyl-polyethyleneglycol conjugate-2000 mPEG2000DSPE
Type Polymer
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
human monocyte-derived macrophages

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]
  • poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol)
  1. aSzEaCT2NaLVe7iXc2uH
Product

nanoformulation of EFV

Z-average diameter: ~ 388 nm

Medium: surfactant solution containing 9.25% sucrose

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]
  • poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol)
  1. 5swrRBBPgeoi6HhxoqUV
Product

nanoformulation of EFV

Z-average diameter: ~ 325 nm

Medium: surfactant solution containing 9.25% sucrose

Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  1. 6LWDwct3FSkKunoQI80HFL
Product

nanoformulation of EFV

Size: not specified

Medium/Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  1. DdlWY03QnwrhfIjMVGiPEN
Product

nanoformulation of EFV

Size: not specified

Medium/Support: none

References

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