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5-fluorouracil-loaded magnetic nanoaggregates

Based on

1 Articles
2012 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

β-cyclodextrin/pluronic F-68-coated magnetic nanoaggregates

Type Nano Material
Formula
Role carriers
2

5-fluoro-2,4(1H,3H)pyrimidinedione

5-fluorouracil 5-Fluorouracil fluorouracil Adrucil® Efudex® adrucil efudex 5-FU 5-Fu 5FU
Type Single Compound
Formula CONHCONHCHCF
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug entrapment efficiency

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Applications

Area Application Nanomaterial Variant Source
drug delivery

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
lung cancer A549 cells

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • 5-fluoro-2,4(1H,3H)pyrimidinedione
  • iron(II) sulphate heptahydrate
  • β-cyclodextrin
See all (5)
  1. W9zBn
  2. YAXrwuW7o9WsxVVJ
  3. MPKd06AH
Product

5-fluorouracil-loaded magnetic nanoaggregates

Size: ~ 74 nm

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  1. eAez2
  2. qEouqV5th7dn5q4E
  3. dZ46bg6F
Product

5-fluorouracil-loaded magnetic nanoaggregates

Size: ~ 74 nm

Medium/Support: none

Method 3

Type: Chemical synthesis
Source:
Starting materials
  • 5-fluoro-2,4(1H,3H)pyrimidinedione
  • iron(II) sulphate heptahydrate
  • β-cyclodextrin
See all (5)
  1. T6SL8
  2. KfmKl6j9ujZkU9nP
  3. pHDehjj8
Product

5-fluorouracil-loaded magnetic nanoaggregates

Size: ~ 82 nm

Medium/Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  1. e0PWy
  2. DFOVxN48gvdHN4Cz
  3. RyS5mgX3
Product

5-fluorouracil-loaded magnetic nanoaggregates

Size: ~ 82 nm

Medium/Support: none

Method 5

Type: Physical formation
Source:
Product

5-fluorouracil-loaded magnetic nanoaggregates

Hydrodynamic diameter: 85.69 - 94.71 nm

Size: ~ 50 nm

Medium: water

Support: none

References

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