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5-fluorouracil-loaded magnetic nanoaggregates

Based on

7 Articles
2016 Most recent source

Composition

1

β-cyclodextrin/pluronic F-68-coated magnetic nanoaggregates

Type Nano Material
Formula
Role carriers
2

5-fluoro-2,4(1H,3H)pyrimidinedione

5-Fluorouracil 5-fluorouracil fluorouracil Adrucil® Efudex® adrucil efudex 5-FU 5-Fu 5FU
Type Single Compound
Formula CONHCONHCHCF
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
accumulated drug release

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Applications

Area Application Nanomaterial Variant Source
drug delivery

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Characterization

Method Nanomaterial Variant Source
atomic force microscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
C57/BL6 murine metastatic melanoma B16F10 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  1. zOY7wybj
  2. 0kS3slZFpmqdaHy6
Product

5-fluorouracil-loaded magnetic nanoaggregates

Size: not specified

Medium/Support: none

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • aluminium(III) chloride hexahydrate
  • magnesium chloride hexahydrate
  • sodium hydroxide
  1. 1mHCj
  2. zOGQfA2m
Product

5-fluorouracil-loaded magnetic nanoaggregates

Hydrodynamic diameter: 50 - 150 nm

Medium: water

Support: none

Method 3

Type: Chemical synthesis
Source:
Starting materials
  • aluminium(III) chloride hexahydrate
  • magnesium chloride hexahydrate
  • sodium hydroxide
  1. xAyat
  2. WyD4khYx
Product

5-fluorouracil-loaded magnetic nanoaggregates

Size: not specified

Medium/Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • 5-fluoro-2,4(1H,3H)pyrimidinedione
  • n-hexadecyl palmitate
  • poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol)
  1. iZRQGIb2H73GCxLt
  2. sKyToLYsxTgrn8OvBioTbSl
  3. BiZcxZIoVvwCQiKulxacio8CMEhoeSmO
Product

5-fluorouracil-loaded magnetic nanoaggregates

Size: 171 - 193 nm

Medium/Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • 5-fluoro-2,4(1H,3H)pyrimidinedione
  • 1-stearoyl-rac-glycerol
  • poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol)
  1. DfnQ7GgLbmF4W7GJ
  2. o7cqoGCaZQfPiiVghPz7K7b
  3. 6jBFcgpuqu4AaFLQ7nGPYQFc9IgsvA64
Product

5-fluorouracil-loaded magnetic nanoaggregates

Size: 144 - 186 nm

Medium/Support: none

References

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