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MTX-loaded Pluronic micelles

Based on

3 Articles
2014 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

pentaerythritol tetraacrylare-cross-linked polyethylene glycol diacrylate

PETRA-cross-linked PEGDA
Type Polymer
Formula
Role carriers
2

methotrexate

abitrexate folex MTX
Type Single Compound
Formula C20H22N8O5
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release dependent on pH

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
breast cancer MCF-7 cells

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  1. yMIacRofQiDPKf
  2. ANoJRao7
Product

MTX-loaded Pluronic micelles

Hydrodynamic diameter: 195 - 255 nm

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) block copolymer
  • methotrexate
  1. rpmge0YdeYoPZ7i36QJ
  2. p3mkpuNSbgbTLg4ikZi
Product

MTX-loaded Pluronic micelles

Hydrodynamic size: 27.44 nm

Medium: water

Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) block copolymer
  • methotrexate
  1. 2cAj5soFeVAFt7s1d6V
  2. SsM9zOn2vPNhlD4p7uf
Product

MTX-loaded Pluronic micelles

Hydrodynamic size: 20.24 nm

Medium: water

Support: none

References

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