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tenofovir/levonorgestrel-loaded combined electrospun nanofibers

Based on

1 Articles
2014 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

poly(vinyl alcohol)

polyvinyl alcohol PVOH PVAI PVA
Type Polymer
Formula
Role raw materials
2

({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)phosphonic acid

({[(2R)-l-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)phosphonic acid (R)-9-(2-phosphonylmethoxypropyl)-adenine (R)-9-[2-(phosphonomethoxy)propyl]adenine tenofovir Viread® PMPA TFV TNF
Type Single Compound
Formula C9H14N5O4P
Role loaded material
3

levonorgestrel

Type Single Compound
Formula C20H27O2
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release dependent on drug concentration

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
confocal laser scanning microscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
TZM-bl cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • poly(vinyl alcohol)
  • levonorgestrel
  • ({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)phosphonic acid
  1. LkaQTde4Vsg2tRSnR
Product

tenofovir/levonorgestrel-loaded combined electrospun nanofibers

Diameter: 168 - 334 nm

Medium/Support: none

References

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