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insulin-loaded biotin-modified liposomes

Based on

1 Articles
2014 Most recent source

Composition

1

citric acid-Na2HPO4 buffer solution

Type Complex Compound
Formula
Role core
2

insulin

Type Biomolecule
Formula
Role loaded material
3

biotin-1,2-distearoyl-sn-glycero-3-phosphatidyl ethanolamine-soybean phosphatidylcholine

biotin-DSPE-SPC
Type Complex Compound
Formula
Role layer
4

cholesterol

Type Single Compound
Formula C27H46O
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
entrapment efficiency

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
transmission electron microscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
Caco-2 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • soybean phosphatidylcholine
  • cholesterol
  • biotin-1,2-distearoyl-sn-glycero-3-phosphatidyl ethanolamine
  1. joQdLHJvO4qr9M
Product

insulin-loaded biotin-modified liposomes

Size: ~ 172 nm

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • soybean phosphatidylcholine
  • cholesterol
  • biotin-1,2-distearoyl-sn-glycero-3-phosphatidyl ethanolamine
  1. Q8IB2VcX4itnuh
Product

insulin-loaded biotin-modified liposomes

Size: 85.6 nm

Medium/Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • soybean phosphatidylcholine
  • cholesterol
  • biotin-1,2-distearoyl-sn-glycero-3-phosphatidyl ethanolamine
  1. MoDNUtcBXX6VBv
Product

insulin-loaded biotin-modified liposomes

Size: ~ 140 nm

Medium/Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • soybean phosphatidylcholine
  • cholesterol
  • biotin-1,2-distearoyl-sn-glycero-3-phosphatidyl ethanolamine
  1. edsZUEYGg0w1Zo
Product

insulin-loaded biotin-modified liposomes

Size: ~ 150 nm

Medium/Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • soybean phosphatidylcholine
  • cholesterol
  • biotin-1,2-distearoyl-sn-glycero-3-phosphatidyl ethanolamine
  1. vDkANxYRUBpL1C
Product

insulin-loaded biotin-modified liposomes

Size: ~ 159 nm

Medium/Support: none

References

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