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silymarin-loaded lipid nanoparticles

Based on

1 Articles
2014 Most recent source

Composition

1

mixture of substance based on (1,3-dioctadecanoylglycerol/1,3-dioctadecanoylglycerol/oleic acid/oleic acid)

Type Complex Compound
Formula
Role core
2

silibinin

silibinin silybin Sm SB
Type Single Compound
Formula C25H22O10
Role fillers
3

mixture of substance based on (polyoxyethylene (20) sorbitan monooleate/egg phosphatidylcholine)

Type Complex Compound
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
beagle dog

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • oleic acid
  • egg phosphatidylcholine
  • silibinin
See all (4)
  1. xRqvFaCJcCru3l54Ne
  2. JyMl
  3. rqjNyX9n2IM3xrDDGH
Product

silymarin-loaded lipid nanoparticles

Hydrodynamic diameter: 121.8 nm

Medium: water

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • oleic acid
  • egg phosphatidylcholine
  • silibinin
See all (4)
  1. 9AoUxPVBZ27MYP5l2c
  2. kBnz
  3. uZ8Q88Azd8j0W3tXhI
Product

silymarin-loaded lipid nanoparticles

Hydrodynamic diameter: ~ 81 nm

Medium: water

Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • oleic acid
  • egg phosphatidylcholine
  • silibinin
See all (4)
  1. DiPFhkGDWRojlGfxB8
  2. AiN2
  3. kIO65oLoOzJlRkL7NI
Product

silymarin-loaded lipid nanoparticles

Hydrodynamic diameter: 71.3 - 86.5 nm

Medium: water

Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • oleic acid
  • egg phosphatidylcholine
  • silibinin
See all (4)
  1. pGOHcWLVXxyBy9JXrW
  2. hYlz
  3. ho4uCLI92aiXK4eXdt
Product

silymarin-loaded lipid nanoparticles

Hydrodynamic diameter: ~ 81 nm

Medium: water

Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • oleic acid
  • egg phosphatidylcholine
  • silibinin
See all (4)
  1. w9I0shSlUVlBuSHmQW
  2. 0ba2
  3. 2U3QsV37IbKIp0eJwZ
Product

silymarin-loaded lipid nanoparticles

Hydrodynamic diameter: ~ 93 nm

Medium: water

Support: none

References

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