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silymarin-loaded lipid nanoparticles

Based on

1 Articles
2014 Most recent source

Composition

1

mixture of substance based on (1,3-dioctadecanoylglycerol/1,3-dioctadecanoylglycerol/oleic acid/oleic acid)

Type Complex Compound
Formula
Role core
2

silymarin

silibinin silybin Sm SB
Type Single Compound
Formula C25H22O10
Role fillers
3

mixture of substance based on (polyoxyethylene (20) sorbitan monooleate/egg phosphatidylcholine)

Type Complex Compound
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
beagle dog

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • silymarin
  • oleic acid
  • egg phosphatidylcholine
See all (4)
  1. J1kK5q8C6Xe9XqAPSP
  2. cGMK
  3. vkn1s9Wge4ruZXKkRt
Product

silymarin-loaded lipid nanoparticles

Hydrodynamic diameter: 121.8 nm

Medium: water

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • silymarin
  • oleic acid
  • egg phosphatidylcholine
See all (4)
  1. lqB6GV6THyr13pl6qt
  2. juzv
  3. Ja9LgJOSlwJXU8Jsus
Product

silymarin-loaded lipid nanoparticles

Hydrodynamic diameter: ~ 81 nm

Medium: water

Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • silymarin
  • oleic acid
  • egg phosphatidylcholine
See all (4)
  1. xcOWx9BwSGVMrUwyI1
  2. 2zuM
  3. 4w9xM2lnVmy9BoSmDa
Product

silymarin-loaded lipid nanoparticles

Hydrodynamic diameter: 71.3 - 86.5 nm

Medium: water

Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • silymarin
  • oleic acid
  • egg phosphatidylcholine
See all (4)
  1. samTQWfxzJ45CJBmkZ
  2. i7GM
  3. 5LVqn14PkRs3D2NXdr
Product

silymarin-loaded lipid nanoparticles

Hydrodynamic diameter: ~ 81 nm

Medium: water

Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • silymarin
  • oleic acid
  • egg phosphatidylcholine
See all (4)
  1. cxUjcjaYbZASDkiF3T
  2. zGxV
  3. 4trzPly35D1vfiLoLZ
Product

silymarin-loaded lipid nanoparticles

Hydrodynamic diameter: ~ 93 nm

Medium: water

Support: none

References

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