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silymarin-loaded lipid nanoparticles

Based on

1 Articles
2014 Most recent source

Composition

1

mixture of substance based on (1,3-dioctadecanoylglycerol/1,3-dioctadecanoylglycerol/oleic acid/oleic acid)

Type Complex Compound
Formula
Role core
2

silymarin

silymarin silybin Sm SB
Type Single Compound
Formula C25H22O10
Role fillers
3

mixture of substance based on (polyoxyethylene (20) sorbitan monooleate/polyoxyethylene (20) sorbitan monooleate/egg phosphatidylcholine/egg phosphatidylcholine)

Type Complex Compound
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
beagle dog

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • silymarin
  • oleic acid
  • egg phosphatidylcholine
See all (4)
  1. 3Frrc80MNJaxmWKt1j
  2. IFMu
  3. ufOFXnT60BTyHg6wtx
Product

silymarin-loaded lipid nanoparticles

Hydrodynamic diameter: ~ 80 nm

Medium: water

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • silymarin
  • oleic acid
  • egg phosphatidylcholine
See all (4)
  1. dT7oVyJs6f12weSf8h
  2. IaBi
  3. G4Yu22Erf2TtJCMBeM
Product

silymarin-loaded lipid nanoparticles

Hydrodynamic diameter: 165.7 nm

Medium: water

Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • silymarin
  • oleic acid
  • egg phosphatidylcholine
See all (4)
  1. 9wcEdHBxAtX8TuSH4z
  2. Wvpj
  3. MMwIiM8t8ysL7YQxdu
Product

silymarin-loaded lipid nanoparticles

Hydrodynamic diameter: ~ 117 nm

Medium: water

Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • silymarin
  • oleic acid
  • egg phosphatidylcholine
See all (4)
  1. eFJD2qsSzV0iQEebQ9
  2. aJhU
  3. kImWFdu0JK8p3oM83O
Product

silymarin-loaded lipid nanoparticles

Hydrodynamic diameter: ~ 75 nm

Medium: water

Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • silymarin
  • oleic acid
  • egg phosphatidylcholine
See all (4)
  1. jyPU76QnMSIXc1IQjk
  2. lnei
  3. 5HjNEwX1g2ai1nPtC9
Product

silymarin-loaded lipid nanoparticles

Hydrodynamic diameter: ~ 81 nm

Medium: water

Support: none

References

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