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curcumin/doxorubicin-loaded methoxy poly(ethylene glycol)-poly(caprolactone) micelles

Based on

1 Articles
2013 Most recent source

Composition

1

monomethoxy poly(ethylene glycol)-poly(ε-caprolactone) diblock copolymer

MPEG-PCL
Type Polymer
Formula
Role raw materials
2

(1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione

(1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione 1,7-bis(4-hydroxy-3-methoxy phenyl)-1,6-heptadiene-3,5-diene 1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione keto form curcumin diferuloylmethane curcumin CCM CUM CUR Cum Cur CM CU Cm
Type Single Compound
Formula C21H20O6
Role loaded material
3

doxorubicin

adriblastin adriamycin DOX DXR
Type Single Compound
Formula C27H29NO11
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
curcumin release

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
C57 mouse infected with LL/2 lung carcinoma

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • (1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione
  • monomethoxy poly(ethylene glycol)-poly(ε-caprolactone) diblock copolymer
  1. GIQV9iL070nEvslYQs
Product

curcumin/doxorubicin-loaded methoxy poly(ethylene glycol)-poly(caprolactone) micelles

Diameter: ~ 27 nm

Hydrodynamic diameter: 37.2 - 39.6 nm

Medium: phosphate buffer solution

Support: none

References

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