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chitosan-siRNA nanoparticles

Based on

1 Articles
2012 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

low molecular weight chitosan

Type Biomolecule
Formula
Role carriers
2

Sjogren syndrome antigen-targeted siRNA

SSB siRNA
Type Biomolecule
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
suspension stability

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
cervical carcinoma HeLa cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • low molecular weight chitosan
  1. oWkHztS6TtOqa6pSjCOD
  2. CTDyhrcrubA
Product

chitosan-siRNA nanoparticles

Size: ~ 160 nm

Medium: 5 mM acetate buffer/4.3 mM sodium sulfite buffer mixture

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • low molecular weight chitosan
  1. RK3RLJbAA3RyIw2u92sB
  2. rxulRH7YMM9
Product

chitosan-siRNA nanoparticles

Size: ~ 201.5 nm

Medium: 5 mM acetate buffer/4.3 mM sodium sulfite buffer mixture

Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • low molecular weight chitosan
  1. AiZVYB2hk51uOStP67F6
  2. K8HiQGErtj6
Product

chitosan-siRNA nanoparticles

Size: ~ 168 nm

Medium: 5 mM acetate buffer/4.3 mM sodium sulfite buffer mixture

Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • low molecular weight chitosan
  1. v6U436yWpdAe90z67d1q
  2. h0Uuge2qKrK
Product

chitosan-siRNA nanoparticles

Size: 202.5 - 212.9 nm

Medium: 5 mM acetate buffer/4.3 mM sodium sulfite buffer mixture

Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • low molecular weight chitosan
  1. 5BlVKYSADXLI4hMavKvU
  2. uFqdFdmtVWL
Product

chitosan-siRNA nanoparticles

Size: ~ 161.1 nm

Medium: 5 mM acetate buffer/4.3 mM sodium sulfite buffer mixture

Support: none

References

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