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silicone oxide-deposited doxorubicin-loaded stearic acid-g-chitosan nanoparticles

Based on

1 Articles
2012 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

stearic acid-g-chitosan conjugate

CS-SA conjugate
Type Complex Compound
Formula
Role core
2

doxorubicin

adriblastin adriamycin DOX DXR
Type Single Compound
Formula C27H29NO11
Role loaded material
3

silicon dioxide

silicic oxide silica
Type Single Compound
Formula SiO2
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
human lung adenocarcinoma A549 cells

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • stearic acid-g-chitosan conjugate
  • doxorubicin
  • water
See all (4)
  1. Uaju
Product

silicone oxide-deposited doxorubicin-loaded stearic acid-g-chitosan nanoparticles

Pore size: 4.3 - 4.9 nm

Medium/Support: none

Method 2

Type: Physical formation
Source:
Product

silicone oxide-deposited doxorubicin-loaded stearic acid-g-chitosan nanoparticles

Hydrodynamic diameter: 35.7 - 36.3 nm

Pore size: 8.0 - 10.2 nm

Medium: water

Support: none

Method 3

Type: Chemical synthesis
Source:
Starting materials
  • stearic acid-g-chitosan conjugate
  • doxorubicin
  • water
See all (4)
  1. sKGI
Product

silicone oxide-deposited doxorubicin-loaded stearic acid-g-chitosan nanoparticles

Size: not specified

Medium/Support: none

Method 4

Type: Physical formation
Source:
Product

silicone oxide-deposited doxorubicin-loaded stearic acid-g-chitosan nanoparticles

Hydrodynamic diameter: 74.1 - 76.3 nm

Pore size: 4.3 - 4.9 nm

Medium: water

Support: none

Method 5

Type: Physical formation
Source:
Product

silicone oxide-deposited doxorubicin-loaded stearic acid-g-chitosan nanoparticles

Hydrodynamic diameter: 55.7 - 56.9 nm

Medium: water

Support: none

References

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