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rhEPO-loaded PEG-PLA micelles

Based on

1 Articles
2013 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

PEG-PLA copolymer

PEG-PLA
Type Polymer
Formula
Role carriers
2

recombinant human erythropoietin

rhEPO
Type Biomolecule
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Applications

Area Application Nanomaterial Variant Source
drug delivery

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
female Sprague-Dawley rats

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • PEG-PLA copolymer
  1. Jutmgvd
  2. eSWn7W33x353MSqT7YGBxJFRA36s
Product

rhEPO-loaded PEG-PLA micelles

Hydrodynamic diameter: 69.8 - 77.0 nm

Medium: phosphate buffer solution

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • PEG-PLA copolymer
  1. gd7wn5s
  2. kFLCkVHFbqtQ2hjWXwmhT5fmtL7Y
Product

rhEPO-loaded PEG-PLA micelles

Hydrodynamic diameter: 68.4 - 71.8 nm

Medium: phosphate buffer solution

Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • PEG-PLA copolymer
  1. KxlTNKX
  2. GY7DpGW3VFkMoDBvaRRLjPvCPUhN
Product

rhEPO-loaded PEG-PLA micelles

Hydrodynamic diameter: 70.6 - 76.2 nm

Size: ~ 20 nm

Medium: phosphate buffer solution

Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • PEG-PLA copolymer
  1. wHzHvm2
  2. CHJYAyHpaIw6eCoA40hDRQjDS4Kt
Product

rhEPO-loaded PEG-PLA micelles

Hydrodynamic diameter: 75.8 - 79.0 nm

Medium: phosphate buffer solution

Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • PEG-PLA copolymer
  1. ANjEwav
  2. 8esG5q8K0dpQeXw1cCTVcaMHFVGs
Product

rhEPO-loaded PEG-PLA micelles

Hydrodynamic diameter: 126.9 - 135.5 nm

Size: ~ 30 nm

Medium: phosphate buffer solution

Support: none

References

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