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docetaxel-loaded PLGA nanoparticles

Based on

1 Articles
2011 Most recent source

Composition

1

poly(lactic-co-glycolic acid)

PLGA
Type Polymer
Formula
Role core
2

poly(vinyl alcohol)

polyvinyl alcohol PVOH PVAI PVA
Type Polymer
Formula
Role layer
3

1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}

docetaxel Taxotere Dtxl Dtx Doc
Type Single Compound
Formula C43H53NO14
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • 1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}
  1. ufSAfwTBBAHZA9dNU3EGDhkC8YLKrH
Product

docetaxel-loaded PLGA nanoparticles

Size: not specified

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • 1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}
  1. COxTX3sSnEycDnfYfalXyYdD2j5hQG
Product

docetaxel-loaded PLGA nanoparticles

Size: not specified

Medium/Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • 1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}
  1. ShGJS0VFX0KNJM5p26pHwMOdiAPOFS
Product

docetaxel-loaded PLGA nanoparticles

Size: not specified

Medium/Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • 1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}
  1. MAGqJoNnR8kzqfDKL3mJoZKMsAoYtt
Product

docetaxel-loaded PLGA nanoparticles

Size: not specified

Medium/Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • 1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}
  1. 2cS2Avjmuxu9uYbGnbxTz2BUOLX4og
Product

docetaxel-loaded PLGA nanoparticles

Size: not specified

Medium/Support: none

References

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