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methotrexate-loaded PLGA nanoparticles in water

Based on

1 Articles
2014 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

poly(lactic-co-glycolic acid)

PLGA
Type Polymer
Formula
Role binder
2

methotrexate

abitrexate folex MTX
Type Single Compound
Formula C20H22N8O5
Role fillers

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
in vitro drug release plot

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Applications

Area Application Nanomaterial Variant Source
drug delivery

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Characterization

Method Nanomaterial Variant Source
differential scanning calorimetry

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Biological effects

Biological system Test details Nanomaterial Variant Source
human neuronal glioblastoma cells U-343 MGa

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • poly(lactic-co-glycolic acid)
  • methotrexate
  1. 4TRLOnKG7ksntRiuaY0xnCQbQceSB
  2. 73kyk4n009
  3. IznCpP6MclOgmUeA6gP15L
  4. CmI3Ueel
Product

methotrexate-loaded PLGA nanoparticles in water

Hydrodynamic size: 194.6 nm

Medium: water

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • poly(lactic-co-glycolic acid)
  • methotrexate
  1. H6GrbnFRovYs5eyD22lwjRddU4WiY
  2. g2RPf1UGjE
  3. ciazLvKxeh52yUgGwlxqMTR
  4. it8msQSi
Product

methotrexate-loaded PLGA nanoparticles in water

Hydrodynamic size: 194.6 nm

Medium: water

Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • poly(lactic-co-glycolic acid)
  • methotrexate
  1. l6XRLkJ9MN418g6SUJzsmYJ9yr9BF
  2. L5MYus6LQB
  3. dafmi7SbcDqOFogoPiVe2A
  4. Ms22vyvI
Product

methotrexate-loaded PLGA nanoparticles in water

Hydrodynamic size: 211.7 nm

Medium: water

Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • poly(lactic-co-glycolic acid)
  • methotrexate
  1. 3rI7bkhNLNvW6zIQ53LQWja7HVEBh
  2. PCTX2yNmse
  3. Dzw1IJaweOjfg9rF3ABZyz
  4. P8Ho2ALD
Product

methotrexate-loaded PLGA nanoparticles in water

Hydrodynamic size: 115.8 nm

Medium: water

Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • poly(lactic-co-glycolic acid)
  • methotrexate
  1. ileGbeXkFpYH0xEfSndVIEsWhx79Q
  2. kcAnKapqKV
  3. M9ZsyMLHve2zl36Y6EJk8iWdluxtCkCo
  4. 81suXpgG
Product

methotrexate-loaded PLGA nanoparticles in water

Hydrodynamic size: 127.0 nm

Medium: water

Support: none

References

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