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methotrexate-loaded PLGA nanoparticles in water

Based on

1 Articles
2014 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

poly(lactic-co-glycolic acid)

PLGA
Type Polymer
Formula
Role binder
2

methotrexate

abitrexate folex MTX
Type Single Compound
Formula C20H22N8O5
Role fillers

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
in vitro drug release plot

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Applications

Area Application Nanomaterial Variant Source
drug delivery

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Characterization

Method Nanomaterial Variant Source
differential scanning calorimetry

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Biological effects

Biological system Test details Nanomaterial Variant Source
human neuronal glioblastoma cells U-343 MGa

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • poly(lactic-co-glycolic acid)
  • methotrexate
  1. WJmMmosi6xoWJitZsJGckaDUcWPpl
  2. IwCXpq9s42
  3. qSif1gdsDQcCwEiROnmFQw
  4. 9yJ5otD3
Product

methotrexate-loaded PLGA nanoparticles in water

Hydrodynamic size: 194.6 nm

Medium: water

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • poly(lactic-co-glycolic acid)
  • methotrexate
  1. oZHhCLwtAiNiOxRcBNkXo9mUqTqBY
  2. HB082vMZ5D
  3. tePErjzn1W13vwjSDiHlZZK
  4. T0L589p8
Product

methotrexate-loaded PLGA nanoparticles in water

Hydrodynamic size: 194.6 nm

Medium: water

Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • poly(lactic-co-glycolic acid)
  • methotrexate
  1. cit4V77kktqpvgAMknwYFh306YVTG
  2. cMaPNiMgil
  3. io40vPC4aoFLr9dMe5tlFI
  4. WOOjB3zx
Product

methotrexate-loaded PLGA nanoparticles in water

Hydrodynamic size: 211.7 nm

Medium: water

Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • poly(lactic-co-glycolic acid)
  • methotrexate
  1. dRWT3dXwh4VPNk76fQHstZA45PkwI
  2. nUaWS4zSOD
  3. 0f0nMzSWJo03JmAvSChu59
  4. sBSTQjb5
Product

methotrexate-loaded PLGA nanoparticles in water

Hydrodynamic size: 115.8 nm

Medium: water

Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • poly(lactic-co-glycolic acid)
  • methotrexate
  1. njD4uLSS1VJvY2bvToUVittX9beuV
  2. YX2dy970bL
  3. nUm5gfDp5RKAKhc2anj0aem2N6whuyVn
  4. 1x5GFR2b
Product

methotrexate-loaded PLGA nanoparticles in water

Hydrodynamic size: 127.0 nm

Medium: water

Support: none

References

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