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chitosan/Poloxamer 188/poly(D,L-lactide-co-glycolide) nanoparticles

Based on

1 Articles
2014 Most recent source

Composition

1

poly(D,L-lactide-co-glycolide)

poly(lactic-co-glycolic acid) PLGA
Type Polymer
Formula
Role binder
2

chitosan

Type Biomolecule
Formula
Role dopant
3

Pluronic® PE 6800

Poloxamer 188 Pluronic F68
Type Polymer
Formula
Role raw materials

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
pCMV-GFP entrapment efficiency dependent on pCMV-GFP concentration

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Applications

Area Application Nanomaterial Variant Source
drug delivery

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
HeLa cell

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • water
  • chitosan
  • Pluronic® PE 6800
  1. f12bF1Y64HgSkjau8eOzKrYki1fG2TV15we7E8lYGcsRTN
Product

chitosan/Poloxamer 188/poly(D,L-lactide-co-glycolide) nanoparticles

Size: 251.1 - 269.7 nm

Medium: water

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • water
  • chitosan
  • Pluronic® PE 6800
  1. SCsF1eVAwu263n1IoPlAz3KSye7w8s6nuz8VcpJ9LlhFar
Product

chitosan/Poloxamer 188/poly(D,L-lactide-co-glycolide) nanoparticles

Size: 163.9 - 176.3 nm

Medium: water

Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • water
  • chitosan
  • Pluronic® PE 6800
  1. i3fOzCHyfR8ACVHVHIx1ecRkGVjkj4Fv2ANm4i4YjfCwjc
Product

chitosan/Poloxamer 188/poly(D,L-lactide-co-glycolide) nanoparticles

Size: 182.1 - 208.5 nm

Medium: water

Support: none

Method 4

Type: Physical formation
Source:
  1. gr223qtrGnP5nsWs8v
Product

chitosan/Poloxamer 188/poly(D,L-lactide-co-glycolide) nanoparticles

Size: ~ 2000 - ~ 3000 nm

Size: ~ 70 nm

Medium: sodium dodecyl sulfate aqueous solution

Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • water
  • chitosan
  • Pluronic® PE 6800
  1. AhlBeYMJRO67CDTDSkyYkxVt7PadbRcm2B6nTEjImm21UQ
Product

chitosan/Poloxamer 188/poly(D,L-lactide-co-glycolide) nanoparticles

Size: 211.8 - 226.8 nm

Medium: water

Support: none

References

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