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paclitaxel nanosuspension

Based on

1 Articles
2011 Most recent source

Composition

1

5β,20-Epoxy-1,2α,4,7β,10β,13α­ hexahydroxytax-11-en-9-one 4,10-diacetate 2-benzoate 13-ester with (2R,3S)-N-benzoyl-3­ phenylisoserine

paclitaxel Paclitaxel Abraxane Plaxicel Paxene Taxol PTX PCL PAC PX
Type Single Compound
Formula C47H51NO14
Role core
2

poloxamer 188/PEG 400

Type Complex Compound
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
dissolution in phosphate-buffered saline

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
differential scanning calorimetry

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Biological effects

Biological system Test details Nanomaterial Variant Source
male imprinting control region (ICR) mouse

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • poly(ethylene glycol) 400
  • poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol)
  1. PSbGzrMFz6g2mDNU
Product

paclitaxel nanosuspension

Size: ~ 242 nm

Medium: water

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
Product

paclitaxel nanosuspension

Size: 199.37 - 229.43 nm

Medium/Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • poly(ethylene glycol) 400
  • poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol)
  1. vrs0W4v3aCDvjlIQ
Product

paclitaxel nanosuspension

Size: ~ 244.7 nm

Medium: water

Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • poly(ethylene glycol) 400
  • poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol)
  1. D3qp7I7lBLxaTZ0X
Product

paclitaxel nanosuspension

Size: ~ 210.5 nm

Medium: water

Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • poly(ethylene glycol) 400
  • poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol)
  1. 7k28TKnyXOtvk7bq
Product

paclitaxel nanosuspension

Size: ~ 216.1 nm

Medium: water

Support: none

References

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