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tamoxifen-loaded hydroxyl-terminated poly(2-methyl-2-oxazoline)-block-poly(dimethylsiloxane)-block-poly(2-methyl-2-oxazoline) nanoparticles

Based on

2 Articles
2015 Most recent source

Composition

1

hydroxyl-terminated poly(2-methyl-2-oxazoline)-block-poly(dimethylsiloxane)-block-poly(2-methyl-2-oxazoline) nanoparticles

hydroxyl-terminated poly(2-methyl-2-oxazoline)-block-poly(dimethylsiloxane)-block-poly(2-methyl-2-oxazoline) micelles OH-PMOXA-b-PDMS-b-PMOXA-OH micelles
Type Nano Material
Formula
Role carriers
2

2-{4-[(1Z)-1,2-diphenylpent-1-en-1-yl]phenoxy}ethyl)dimethylamine

Tamoxifen citrate Tamoxifen tamoxifen TAM TMF TMX TmC
Type Single Compound
Formula C26H29NO
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release dependent on drug loading

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Applications

Area Application Nanomaterial Variant Source
diagnostics

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Characterization

Method Nanomaterial Variant Source
differential scanning calorimetry

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Biological effects

Biological system Test details Nanomaterial Variant Source
C57BL/6 mouse

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  1. w6wMAShpcKd7mQe5x7v1bS780L
Product

tamoxifen-loaded hydroxyl-terminated poly(2-methyl-2-oxazoline)-block-poly(dimethylsiloxane)-block-poly(2-methyl-2-oxazoline) nanoparticles

Size: not specified

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  1. AJdJGgofxS4cBxxQqzBhDlVg4B
Product

tamoxifen-loaded hydroxyl-terminated poly(2-methyl-2-oxazoline)-block-poly(dimethylsiloxane)-block-poly(2-methyl-2-oxazoline) nanoparticles

Size: not specified

Medium/Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • poly(amidoamine)-cholesterol conjugate
  • 2-{4-[(1Z)-1,2-diphenylpent-1-en-1-yl]phenoxy}ethyl)dimethylamine
  1. mgeQvqeZm0
  2. rEG0cL8bzRRgHT0WQevCjqwvcSUKhvZan6fYA5
  3. FWCsHRUOkhXnb2Kiku1hm
Product

tamoxifen-loaded hydroxyl-terminated poly(2-methyl-2-oxazoline)-block-poly(dimethylsiloxane)-block-poly(2-methyl-2-oxazoline) nanoparticles

Diameter: 211.6 - 282.4 nm

Medium/Support: none

References

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