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Gd(III)-DOTA-G5-FA nanoparticles

Based on

1 Articles
2008 Most recent source

Composition

1

G5 polyamidoamine

PAMAM-NH2 PAMAM G5
Type Polymer
Formula
Role core
2

pteroylglutamic acidan

pteroylglutamic acid folic acid PGA FA
Type Single Compound
Formula C19H19N7O6
Role graft
3

1,4,7,10-tetraazacyclododecane, α-[5-isothiocyanato-2-methoxyphenyl]-, hydrochloride [9Cl]

DOTA-NCS
Type Single Compound
Formula C16H26ClN5OS
Role layer
4

gadolinium atom

gadolinium
Type Single Compound
Formula Gd
Role loaded material
5

carbonyl moiety

acetyl fragment acetyl group acetyl
Type Single Compound
Formula -C2H3O
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
magnetic resonance imaging relaxivity

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Biological effects

Biological system Test details Nanomaterial Variant Source
NOD C.B-17 SCID mice using human KB tumor cells over-expressing folate receptor

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • G5 polyamidoamine
  • pteroylglutamic acidan
  1. c5zpywbPtALa6LlIvK4PLQI6HNNgL
  2. MZ7R
  3. One
Product

Gd(III)-DOTA-G5-FA nanoparticles

Size: not specified

Medium/Support: none

References

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